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DNA Replication Dynamics of the GGGGCC Repeat of the C9orf72 Gene

DNA has the ability to form a variety of secondary structures in addition to the normal B-form DNA, including hairpins and quadruplexes. These structures are implicated in a number of neurological diseases and cancer. Expansion of a GGGGCC repeat located at C9orf72 is associated with familial amyotr...

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Detalles Bibliográficos
Autores principales: Thys, Ryan Griffin, Wang, Yuh-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661408/
https://www.ncbi.nlm.nih.gov/pubmed/26463209
http://dx.doi.org/10.1074/jbc.M115.660324