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DNA Replication Dynamics of the GGGGCC Repeat of the C9orf72 Gene
DNA has the ability to form a variety of secondary structures in addition to the normal B-form DNA, including hairpins and quadruplexes. These structures are implicated in a number of neurological diseases and cancer. Expansion of a GGGGCC repeat located at C9orf72 is associated with familial amyotr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661408/ https://www.ncbi.nlm.nih.gov/pubmed/26463209 http://dx.doi.org/10.1074/jbc.M115.660324 |