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Phospholipase Cη2 Activation Redirects Vesicle Trafficking by Regulating F-actin

PI(4,5)P(2) localizes to sites of dense core vesicle exocytosis in neuroendocrine cells and is required for Ca(2+)-triggered vesicle exocytosis, but the impact of local PI(4,5)P(2) hydrolysis on exocytosis is poorly understood. Previously, we reported that Ca(2+)-dependent activation of phospholipas...

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Detalles Bibliográficos
Autores principales: Yamaga, Masaki, Kielar-Grevstad, D. Michelle, Martin, Thomas F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661413/
https://www.ncbi.nlm.nih.gov/pubmed/26432644
http://dx.doi.org/10.1074/jbc.M115.658328