Cargando…

Probing protein interactions in living mammalian cells on a microtubule bench

Microtubules are μm-long cylinders of about 25 nm in diameter which are present in the cytoplasm of eukaryotic cells. Here, we have developed a new method which uses these cylindrical structures as platforms to detect protein interactions in cells. The principle is simple: a protein of interest used...

Descripción completa

Detalles Bibliográficos
Autores principales: Boca, Mirela, Kretov, Dmitry A., Desforges, Bénédicte, Mephon-Gaspard, Alix, Curmi, Patrick A., Pastré, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661529/
https://www.ncbi.nlm.nih.gov/pubmed/26610591
http://dx.doi.org/10.1038/srep17304