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MicroRNA-222 regulates MMP-13 via targeting HDAC-4 during osteoarthritis pathogenesis

BACKGROUND: Even though increasing evidences on miRNA involvement in human pathological responses, the distinct roles and related mechanisms of miRNAs in the pathology of osteoarthritis (OA) are not yet fully understood. METHOD: RNA levels or protein levels of Apoptotic genes, HDACs, MMP-13, and miR...

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Detalles Bibliográficos
Autores principales: Song, Jinsoo, Jin, Eun-Heui, Kim, Dongkyun, Kim, Keun Young, Chun, Churl-Hong, Jin, Eun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661531/
https://www.ncbi.nlm.nih.gov/pubmed/26673737
http://dx.doi.org/10.1016/j.bbacli.2014.11.009