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MicroRNA-222 regulates MMP-13 via targeting HDAC-4 during osteoarthritis pathogenesis
BACKGROUND: Even though increasing evidences on miRNA involvement in human pathological responses, the distinct roles and related mechanisms of miRNAs in the pathology of osteoarthritis (OA) are not yet fully understood. METHOD: RNA levels or protein levels of Apoptotic genes, HDACs, MMP-13, and miR...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661531/ https://www.ncbi.nlm.nih.gov/pubmed/26673737 http://dx.doi.org/10.1016/j.bbacli.2014.11.009 |