Truncated HSPB1 causes axonal neuropathy and impairs tolerance to unfolded protein stress

BACKGROUND: HSPB1 belongs to the family of small heat shock proteins (sHSP) that have importance in protection against unfolded protein stress, in cancer cells for escaping drug toxicity stress and in neurons for suppression of protein aggregates. sHSPs have a conserved α-crystalline domain (ACD), f...

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Detalles Bibliográficos
Autores principales: Ylikallio, Emil, Konovalova, Svetlana, Dhungana, Yogesh, Hilander, Taru, Junna, Nella, Partanen, Juhani V., Toppila, Jussi P., Auranen, Mari, Tyynismaa, Henna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661565/
https://www.ncbi.nlm.nih.gov/pubmed/26675522
http://dx.doi.org/10.1016/j.bbacli.2015.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661565/
https://www.ncbi.nlm.nih.gov/pubmed/26675522
http://dx.doi.org/10.1016/j.bbacli.2015.03.002

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