Conservation and Role of Electrostatics in Thymidylate Synthase

Conservation of function across families of orthologous enzymes is generally accompanied by conservation of their active site electrostatic potentials. To study the electrostatic conservation in the highly conserved essential enzyme, thymidylate synthase (TS), we conducted a systematic species-based...

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Detalles Bibliográficos
Autores principales: Garg, Divita, Skouloubris, Stephane, Briffotaux, Julien, Myllykallio, Hannu, Wade, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661567/
https://www.ncbi.nlm.nih.gov/pubmed/26612036
http://dx.doi.org/10.1038/srep17356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661567/
https://www.ncbi.nlm.nih.gov/pubmed/26612036
http://dx.doi.org/10.1038/srep17356

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