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A Discriminant Function Approach to Adjust for Processing and Measurement Error When a Biomarker is Assayed in Pooled Samples

Pooling biological specimens prior to performing expensive laboratory assays has been shown to be a cost effective approach for estimating parameters of interest. In addition to requiring specialized statistical techniques, however, the pooling of samples can introduce assay errors due to processing...

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Detalles Bibliográficos
Autores principales: Lyles, Robert H., Van Domelen, Dane, Mitchell, Emily M., Schisterman, Enrique F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661676/
https://www.ncbi.nlm.nih.gov/pubmed/26593934
http://dx.doi.org/10.3390/ijerph121114723