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Pooling Bio-Specimens in the Presence of Measurement Error and Non-Linearity in Dose-Response: Simulation Study in the Context of a Birth Cohort Investigating Risk Factors for Autism Spectrum Disorders

We sought to determine the potential effects of pooling on power, false positive rate (FPR), and bias of the estimated associations between hypothetical environmental exposures and dichotomous autism spectrum disorders (ASD) status. Simulated birth cohorts in which ASD outcome was assumed to have be...

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Detalles Bibliográficos
Autores principales: Heavner, Karyn, Newschaffer, Craig, Hertz-Picciotto, Irva, Bennett, Deborah, Burstyn, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661679/
https://www.ncbi.nlm.nih.gov/pubmed/26610532
http://dx.doi.org/10.3390/ijerph121114780