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Development of Endothelial-Specific Single Inducible Lentiviral Vectors for Genetic Engineering of Endothelial Progenitor Cells

Endothelial progenitor cells (EPC) are able to migrate to tumor vasculature. These cells, if genetically modified, can be used as vehicles to deliver toxic material to, or express anticancer proteins in tumor. To test this hypothesis, we developed several single, endothelial-specific, and doxycyclin...

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Detalles Bibliográficos
Autores principales: Yang, Guanghua, Kramer, M. Gabriela, Fernandez-Ruiz, Veronica, Kawa, Milosz P., Huang, Xin, Liu, Zhongmin, Prieto, Jesus, Qian, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661691/
https://www.ncbi.nlm.nih.gov/pubmed/26612671
http://dx.doi.org/10.1038/srep17166