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Evaluation of New Fluorescent Lipophosphoramidates for Gene Transfer and Biodistribution Studies after Systemic Administration

The objective of lung gene therapy is to reach the respiratory epithelial cells in order to deliver a functional nucleic acid sequence. To improve the synthetic carrier’s efficacy, knowledge of their biodistribution and elimination pathways, as well as cellular barriers faced, depending on the admin...

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Detalles Bibliográficos
Autores principales: Belmadi, Nawal, Berchel, Mathieu, Denis, Caroline, Berthe, Wilfried, Sibiril, Yann, Le Gall, Tony, Haelters, Jean-Pierre, Jaffres, Paul-Alain, Montier, Tristan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661800/
https://www.ncbi.nlm.nih.gov/pubmed/26540038
http://dx.doi.org/10.3390/ijms161125941