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Notch Cooperates with Survivin to Maintain Stemness and to Stimulate Proliferation in Human Keratinocytes during Ageing

The Notch signaling pathway orchestrates cell fate by either inducing cell differentiation or maintaining cells in an undifferentiated state. This study aims to evaluate Notch expression and function in normal human keratinocytes. Notch1 is expressed in all epidermal layers, though to a different de...

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Detalles Bibliográficos
Autores principales: Palazzo, Elisabetta, Morandi, Paolo, Lotti, Roberta, Saltari, Annalisa, Truzzi, Francesca, Schnebert, Sylvianne, Dumas, Marc, Marconi, Alessandra, Pincelli, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661807/
https://www.ncbi.nlm.nih.gov/pubmed/26540052
http://dx.doi.org/10.3390/ijms161125948