Comparison of Simple Eudragit Microparticles Loaded with Prednisolone and Eudragit-Coated Chitosan-Succinyl-Prednisolone Conjugate Microparticles: Part II. In Vivo Evaluation of Efficacy, Toxicity, and Biodisposition Characteristics

We previously prepared and evaluated simple Eudragit S100 microparticles loaded with prednisolone (ES-MP) and Eudragit S100-coated chitosan-succinyl-prednisolone conjugate microparticles (Ch-MP/ES) in vitro. In this work, the effectiveness, toxic side effects (5 mg prednisolone (PD) eq/kg × 3 d, 10...

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Detalles Bibliográficos
Autores principales: Onishi, Hiraku, Kikuchi, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661808/
https://www.ncbi.nlm.nih.gov/pubmed/26540041
http://dx.doi.org/10.3390/ijms161125949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661808/
https://www.ncbi.nlm.nih.gov/pubmed/26540041
http://dx.doi.org/10.3390/ijms161125949

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