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Accumulation and Phosphorylation of RecQ-Mediated Genome Instability Protein 1 (RMI1) at Serine 284 and Serine 292 during Mitosis

Chromosome instability usually leads to tumorigenesis. Bloom syndrome (BS) is a genetic disease associated with chromosome instability. The BS gene product, BLM, has been reported to function in the spindle assembly checkpoint (SAC) to prevent chromosome instability. BTR complex, composed of BLM, to...

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Detalles Bibliográficos
Autores principales: Xu, Chang, Wang, Yan, Wang, Lu, Wang, Qin, Du, Li-Qing, Fan, Saijun, Liu, Qiang, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661824/
https://www.ncbi.nlm.nih.gov/pubmed/26556339
http://dx.doi.org/10.3390/ijms161125965