Protein Recognition in Drug-Induced DNA Alkylation: When the Moonlight Protein GAPDH Meets S23906-1/DNA Minor Groove Adducts

DNA alkylating drugs have been used in clinics for more than seventy years. The diversity of their mechanism of action (major/minor groove; mono-/bis-alkylation; intra-/inter-strand crosslinks; DNA stabilization/destabilization, etc.) has undoubtedly major consequences on the cellular response to tr...

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Detalles Bibliográficos
Autores principales: Savreux-Lenglet, Gaëlle, Depauw, Sabine, David-Cordonnier, Marie-Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661830/
https://www.ncbi.nlm.nih.gov/pubmed/26556350
http://dx.doi.org/10.3390/ijms161125971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661830/
https://www.ncbi.nlm.nih.gov/pubmed/26556350
http://dx.doi.org/10.3390/ijms161125971

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