Sildenafil Protects against Myocardial Ischemia-Reperfusion Injury Following Cardiac Arrest in a Porcine Model: Possible Role of the Renin-Angiotensin System

Sildenafil, a phosphodiesterase-5 inhibitor sold as Viagra, is a cardioprotector against myocardial ischemia/reperfusion (I/R) injury. Our study explored whether sildenafil protects against I/R-induced damage in a porcine cardiac arrest and resuscitation (CAR) model via modulating the renin-angioten...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Guoxing, Zhang, Qian, Yuan, Wei, Wu, Junyuan, Li, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661868/
https://www.ncbi.nlm.nih.gov/pubmed/26569234
http://dx.doi.org/10.3390/ijms161126010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661868/
https://www.ncbi.nlm.nih.gov/pubmed/26569234
http://dx.doi.org/10.3390/ijms161126010

Ejemplares similares