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Application of Wnt Pathway Inhibitor Delivering Scaffold for Inhibiting Fibrosis in Urethra Strictures: In Vitro and in Vivo Study

Objective: To evaluate the mechanical property and biocompatibility of the Wnt pathway inhibitor (ICG-001) delivering collagen/poly(l-lactide-co-caprolactone) (P(LLA-CL)) scaffold for urethroplasty, and also the feasibility of inhibiting the extracellular matrix (ECM) expression in vitro and in vivo...

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Detalles Bibliográficos
Autores principales: Zhang, Kaile, Guo, Xuran, Zhao, Weixin, Niu, Guoguang, Mo, Xiumei, Fu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661908/
https://www.ncbi.nlm.nih.gov/pubmed/26610467
http://dx.doi.org/10.3390/ijms161126050