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Borneol Depresses P-Glycoprotein Function by a NF-κB Signaling Mediated Mechanism in a Blood Brain Barrier in Vitro Model

P-glycoprotein (P-gp) on brain microvascular endothelial cells (BMECs) that form the blood brain barrier (BBB), influences transportation of substances between blood and brain. The objective of this study was to characterize the effects of borneol on P-gp efflux function on BBB and explore the poten...

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Detalles Bibliográficos
Autores principales: Fan, Xiang, Chai, Lijuan, Zhang, Han, Wang, Yuefei, Zhang, Boli, Gao, Xiumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661909/
https://www.ncbi.nlm.nih.gov/pubmed/26593909
http://dx.doi.org/10.3390/ijms161126051