Cargando…
Borneol Depresses P-Glycoprotein Function by a NF-κB Signaling Mediated Mechanism in a Blood Brain Barrier in Vitro Model
P-glycoprotein (P-gp) on brain microvascular endothelial cells (BMECs) that form the blood brain barrier (BBB), influences transportation of substances between blood and brain. The objective of this study was to characterize the effects of borneol on P-gp efflux function on BBB and explore the poten...
Autores principales: | Fan, Xiang, Chai, Lijuan, Zhang, Han, Wang, Yuefei, Zhang, Boli, Gao, Xiumei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661909/ https://www.ncbi.nlm.nih.gov/pubmed/26593909 http://dx.doi.org/10.3390/ijms161126051 |
Ejemplares similares
-
The Role and Mechanism of Borneol to Open the Blood-Brain
Barrier
por: Wu, Tao, et al.
Publicado: (2018) -
Borneol and Tetrandrine Modulate the Blood–Brain Barrier and
Blood–Tumor Barrier to Improve the Therapeutic Efficacy of 5-Fluorouracil in
Brain Metastasis
por: Lin, Jui-Feng, et al.
Publicado: (2022) -
Borneol Attenuates Ultrasound-Targeted Microbubble Destruction-Induced Blood–Brain Barrier Opening in Focal Cerebral Ischemia
por: Zhang, Xiao-guang, et al.
Publicado: (2017) -
Enhanced permeability of blood–brain barrier and targeting function of brain via borneol-modified chemically solid lipid nanoparticle
por: Song, Hui, et al.
Publicado: (2018) -
Borneol, a novel agent that improves central nervous system drug delivery by enhancing blood–brain barrier permeability
por: Zhang, Qun-Lin, et al.
Publicado: (2017)