Epigenetic Repression of miR-218 Promotes Esophageal Carcinogenesis by Targeting ROBO1

miR-218, consisting of miR-218-1 at 4p15.31 and miR-218-2 at 5q35.1, was significantly decreased in esophageal squamous cell carcinoma (ESCC) in our previous study. The aim of this study was to determine whether aberrant methylation is associated with miR-218 repression. Bisulfite sequencing analysi...

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Detalles Bibliográficos
Autores principales: Yang, Miao, Liu, Ran, Li, Xiajun, Liao, Juan, Pu, Yuepu, Pan, Enchun, Wang, Yi, Yin, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661920/
https://www.ncbi.nlm.nih.gov/pubmed/26610476
http://dx.doi.org/10.3390/ijms161126062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661920/
https://www.ncbi.nlm.nih.gov/pubmed/26610476
http://dx.doi.org/10.3390/ijms161126062

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