Nucleotide-Induced Conformational Changes in Escherichia coli DnaA Protein Are Required for Bacterial ORC to Pre-RC Conversion at the Chromosomal Origin

DnaA oligomerizes when bound to origins of chromosomal replication. Structural analysis of a truncated form of DnaA from Aquifex aeolicus has provided insight into crucial conformational differences within the AAA+ domain that are specific to the ATP- versus ADP- bound form of DnaA. In this study mo...

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Detalles Bibliográficos
Autores principales: Saxena, Rahul, Vasudevan, Sona, Patil, Digvijay, Ashoura, Norah, Grimwade, Julia E., Crooke, Elliott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661922/
https://www.ncbi.nlm.nih.gov/pubmed/26610483
http://dx.doi.org/10.3390/ijms161126064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661922/
https://www.ncbi.nlm.nih.gov/pubmed/26610483
http://dx.doi.org/10.3390/ijms161126064

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