Tuneable endogenous mammalian target complementation via multiplexed plasmid-based recombineering

Understanding the quantitative functional consequences of human disease mutations requires silencing of endogenous genes and expression of mutants at close to physiological levels. Changing protein levels above or below these levels is also important for system perturbation and modelling. Fast desig...

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Detalles Bibliográficos
Autores principales: Beltran-Sastre, Violeta, Benisty, Hannah, Burnier, Julia, Berger, Imre, Serrano, Luis, Kiel, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661934/
https://www.ncbi.nlm.nih.gov/pubmed/26612112
http://dx.doi.org/10.1038/srep17432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661934/
https://www.ncbi.nlm.nih.gov/pubmed/26612112
http://dx.doi.org/10.1038/srep17432

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