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STAT1 inhibits human hepatocellular carcinoma cell growth through induction of p53 and Fbxw7

BACKGROUND: Aberrant STAT1 signaling is observed in human hepatocellular carcinoma (HCC) and has been associated with the modulation of cell proliferation and survival. However, the role of STAT1 signaling in HCC and its underlying mechanism remain elusive. METHODS: We transiently transfected pcDNA3...

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Detalles Bibliográficos
Autores principales: Chen, Jiayu, Wang, Haihe, Wang, Jing, Huang, Shishun, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661940/
https://www.ncbi.nlm.nih.gov/pubmed/26617467
http://dx.doi.org/10.1186/s12935-015-0253-6