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Ascorbate-dependent vasopressor synthesis: a rationale for vitamin C administration in severe sepsis and septic shock?

Severe systemic inflammatory response to infection results in severe sepsis and septic shock, which are the leading causes of death in critically ill patients. Septic shock is characterised by refractory hypotension and is typically managed by fluid resuscitation and administration of catecholamine...

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Detalles Bibliográficos
Autores principales: Carr, Anitra C., Shaw, Geoffrey M., Fowler, Alpha A., Natarajan, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661979/
https://www.ncbi.nlm.nih.gov/pubmed/26612352
http://dx.doi.org/10.1186/s13054-015-1131-2