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Neuroprotective effects of Cerebrolysin in triple repeat Tau transgenic model of Pick’s disease and fronto-temporal tauopathies

BACKGROUND: Tauopathies are a group of neurodegenerative disorders with accumulation of three-repeat (3R) or four-repeat (4R) Tau. While 3R tau is found in Pick’s disease and Alzheimer’s disease (AD), 4R tau is more abundant in corticobasal degeneration, progressive supranuclear palsy, and AD. We ha...

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Detalles Bibliográficos
Autores principales: Rockenstein, Edward, Ubhi, Kiren, Mante, Michael, Florio, Jazmin, Adame, Anthony, Winter, Stefan, Brandstaetter, Hemma, Meier, Dieter, Masliah, Eliezer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662012/
https://www.ncbi.nlm.nih.gov/pubmed/26611895
http://dx.doi.org/10.1186/s12868-015-0218-7