Polo-like kinase 2 acting as a promoter in human tumor cells with an abundance of TAp73

BACKGROUND: TAp73, a member of the p53 tumor suppressor family, is frequently overexpressed in malignant tumors in humans. TAp73 abundance and phosphorylation modification result in variations in transcriptional activity. In a previous study, we found that the antitumor function of TAp73 was reactiv...

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Detalles Bibliográficos
Autores principales: Hu, ZhengBo, Xu, ZunYing, Liao, XiaoHong, Yang, Xiao, Dong, Cao, Luk, KuaDi, Jin, AnMin, Lu, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662374/
https://www.ncbi.nlm.nih.gov/pubmed/26640387
http://dx.doi.org/10.2147/OTT.S90302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662374/
https://www.ncbi.nlm.nih.gov/pubmed/26640387
http://dx.doi.org/10.2147/OTT.S90302

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