Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration

Fatty acid synthase (FASN), a lipogenic enzyme, is upregulated in colorectal cancer (CRC). Increased de novo lipid synthesis is thought to be a metabolic adaptation of cancer cells that promotes survival and metastasis; however, the mechanisms for this phenomenon are not fully understood. We show th...

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Detalles Bibliográficos
Autores principales: Zaytseva, Yekaterina Y., Harris, Jennifer W., Mitov, Mihail I., Kim, Ji Tae, Butterfield, D. Allan, Lee, Eun Y., Weiss, Heidi L., Gao, Tianyan, Evers, B. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662462/
https://www.ncbi.nlm.nih.gov/pubmed/25970773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662462/
https://www.ncbi.nlm.nih.gov/pubmed/25970773

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