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Nitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activity

Cathepsin B is a ubiquitously expressed lysosomal cysteine protease that participates in protein turnover within lysosomes. However, its protein and activity levels have been shown to be increased in cancer. Cathepsin B endopeptidase activity is involved in the degradation of extracellular matrix, a...

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Detalles Bibliográficos
Autores principales: Mirković, Bojana, Markelc, Boštjan, Butinar, Miha, Mitrović, Ana, Sosič, Izidor, Gobec, Stanislav, Vasiljeva, Olga, Turk, Boris, Čemažar, Maja, Serša, Gregor, Kos, Janko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662473/
https://www.ncbi.nlm.nih.gov/pubmed/25848918