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Nitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activity
Cathepsin B is a ubiquitously expressed lysosomal cysteine protease that participates in protein turnover within lysosomes. However, its protein and activity levels have been shown to be increased in cancer. Cathepsin B endopeptidase activity is involved in the degradation of extracellular matrix, a...
Autores principales: | Mirković, Bojana, Markelc, Boštjan, Butinar, Miha, Mitrović, Ana, Sosič, Izidor, Gobec, Stanislav, Vasiljeva, Olga, Turk, Boris, Čemažar, Maja, Serša, Gregor, Kos, Janko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662473/ https://www.ncbi.nlm.nih.gov/pubmed/25848918 |
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