Gα(12) overexpressed in hepatocellular carcinoma reduces microRNA-122 expression via HNF4α inactivation, which causes c-Met induction

MicroRNA-122 (miR-122) is implicated as a regulator of physiological and pathophysiological processes in the liver. Overexpression of Gα(12) is associated with overall survival in patients with hepatocellular carcinoma (HCC). Array-based miRNA profiling was performed on Huh7 stably transfected with...

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Detalles Bibliográficos
Autores principales: Yang, Yoon Mee, Lee, Chan Gyu, Koo, Ja Hyun, Kim, Tae Hyun, Lee, Jung Min, An, Jihyun, Kim, Kang Mo, Kim, Sang Geon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662475/
https://www.ncbi.nlm.nih.gov/pubmed/25965999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662475/
https://www.ncbi.nlm.nih.gov/pubmed/25965999

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