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A novel HMGA1-CCNE2-YAP axis regulates breast cancer aggressiveness

High Mobility Group A1 (HMGA1) is an architectural chromatin factor that promotes neoplastic transformation and progression. However, the mechanism by which HMGA1 exerts its oncogenic function is not fully understood. Here, we show that cyclin E2 (CCNE2) acts downstream of HMGA1 to regulate the moti...

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Detalles Bibliográficos
Autores principales: Pegoraro, Silvia, Ros, Gloria, Ciani, Yari, Sgarra, Riccardo, Piazza, Silvano, Manfioletti, Guidalberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662477/
https://www.ncbi.nlm.nih.gov/pubmed/26265440