The SIRT1/TP53 axis is activated upon B-cell receptor triggering via miR-132 up-regulation in chronic lymphocytic leukemia cells

The B-cell receptor (BCR) plays an important role in the pathogenesis and progression of chronic lymphocytic leukemia (CLL). By global microRNA profiling of CLL cells stimulated or not stimulated by anti-IgM, significant up-regulation of microRNAs from the miR-132~212 cluster was observed both in IG...

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Detalles Bibliográficos
Autores principales: Dal Bo, Michele, D'Agaro, Tiziana, Gobessi, Stefania, Zucchetto, Antonella, Dereani, Sara, Rossi, Davide, Zaja, Francesco, Pozzato, Gabriele, Di Raimondo, Francesco, Gaidano, Gianluca, Laurenti, Luca, Del Poeta, Giovanni, Efremov, Dimitar G., Gattei, Valter, Bomben, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662478/
https://www.ncbi.nlm.nih.gov/pubmed/26036258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662478/
https://www.ncbi.nlm.nih.gov/pubmed/26036258

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