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The SIRT1/TP53 axis is activated upon B-cell receptor triggering via miR-132 up-regulation in chronic lymphocytic leukemia cells
The B-cell receptor (BCR) plays an important role in the pathogenesis and progression of chronic lymphocytic leukemia (CLL). By global microRNA profiling of CLL cells stimulated or not stimulated by anti-IgM, significant up-regulation of microRNAs from the miR-132~212 cluster was observed both in IG...
Autores principales: | Dal Bo, Michele, D'Agaro, Tiziana, Gobessi, Stefania, Zucchetto, Antonella, Dereani, Sara, Rossi, Davide, Zaja, Francesco, Pozzato, Gabriele, Di Raimondo, Francesco, Gaidano, Gianluca, Laurenti, Luca, Del Poeta, Giovanni, Efremov, Dimitar G., Gattei, Valter, Bomben, Riccardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662478/ https://www.ncbi.nlm.nih.gov/pubmed/26036258 |
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