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Protein phosphatase PHLPP induces cell apoptosis and exerts anticancer activity by inhibiting Survivin phosphorylation and nuclear export in gallbladder cancer

Many factors regulate cancer cell apoptosis, among which Survivin has a strong anti-apoptotic effect and PHLPP is a tumor suppressor gene that can induce significant apoptosis. However, the relationship between PHLPP and Survivin in gallbladder carcinoma (GBC) has not been reported. This study found...

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Detalles Bibliográficos
Autores principales: Qiu, Yinghe, Li, Xiaoya, Yi, Bin, Zheng, Junnian, Peng, Zhangxiao, Zhang, Zhihan, Wu, Mengchao, Shen, Feng, Su, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662481/
https://www.ncbi.nlm.nih.gov/pubmed/25895131