EMT is not required for lung metastasis but contributes to chemoresistance

The role of epithelial to mesenchymal transition (EMT) in metastasis is a longstanding source of controversy, largely due to an inability to monitor transient and reversible EMT phenotypes in vivo. We established an EMT lineage tracing system to monitor this process, using a mesenchymal-specific Cre...

Descripción completa

Detalles Bibliográficos
Autores principales: Fischer, Kari R., Durrans, Anna, Lee, Sharrell, Sheng, Jianting, Li, Fuhai, Wong, Stephen, Choi, Hyejin, El Rayes, Tina, Ryu, Seongho, Troeger, Juliane, Schwabe, Robert F., Vahdat, Linda T., Altorki, Nasser K., Mittal, Vivek, Gao, Dingcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662610/
https://www.ncbi.nlm.nih.gov/pubmed/26560033
http://dx.doi.org/10.1038/nature15748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662610/
https://www.ncbi.nlm.nih.gov/pubmed/26560033
http://dx.doi.org/10.1038/nature15748

Ejemplares similares