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Circulating ghrelin level is higher in HNF1A–MODY and GCK–MODY than in polygenic forms of diabetes mellitus

Ghrelin is a hormone that regulates appetite. It is likely to be involved in the pathophysiology of varying forms of diabetes. In animal studies, the ghrelin expression was regulated by the hepatocyte nuclear factor 1 alpha (HNF1A). Mutations of the HNF1A gene cause maturity onset diabetes of the yo...

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Detalles Bibliográficos
Autores principales: Nowak, Natalia, Hohendorff, Jerzy, Solecka, Iwona, Szopa, Magdalena, Skupien, Jan, Kiec-Wilk, Beata, Mlynarski, Wojciech, Malecki, Maciej T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662709/
https://www.ncbi.nlm.nih.gov/pubmed/25987348
http://dx.doi.org/10.1007/s12020-015-0627-5