Extracellular rigidity sensing by talin isoform–specific mechanical linkages

The ability of cells to adhere and sense differences in tissue stiffness is crucial for organ development and function. The central mechanisms by which adherent cells detect extracellular matrix compliance, however, are still unknown. Using two single-molecule–calibrated biosensors that allow the an...

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Detalles Bibliográficos
Autores principales: Austen, Katharina, Ringer, Pia, Mehlich, Alexander, Chrostek-Grashoff, Anna, Kluger, Carleen, Klingner, Christoph, Sabass, Benedikt, Zent, Roy, Rief, Matthias, Grashoff, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662888/
https://www.ncbi.nlm.nih.gov/pubmed/26523364
http://dx.doi.org/10.1038/ncb3268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662888/
https://www.ncbi.nlm.nih.gov/pubmed/26523364
http://dx.doi.org/10.1038/ncb3268

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