Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives

Fibrillar aggregates of human islet amyloid polypeptide, hIAPP, a pathological feature seen in some diabetes patients, are a likely causative agent for pancreatic beta-cell toxicity, leading to a transition from a state of insulin resistance to type II diabetes through the loss of insulin producing...

Descripción completa

Detalles Bibliográficos
Autores principales: Pithadia, Amit, Brender, Jeffrey R., Fierke, Carol A., Ramamoorthy, Ayyalusamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662995/
https://www.ncbi.nlm.nih.gov/pubmed/26649317
http://dx.doi.org/10.1155/2016/2046327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662995/
https://www.ncbi.nlm.nih.gov/pubmed/26649317
http://dx.doi.org/10.1155/2016/2046327

Ejemplares similares