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HDAC6 Regulates the Chaperone-Mediated Autophagy to Prevent Oxidative Damage in Injured Neurons after Experimental Spinal Cord Injury

Hypoxia-ischemia- (HI-) induced oxidative stress plays a role in secondary pathocellular processes of acute spinal cord injury (SCI) due to HI from many kinds of mechanical trauma. Increasing evidence suggests that the histone deacetylase-6 (HDAC6) plays an important role in cell homeostasis in both...

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Detalles Bibliográficos
Autores principales: Su, Min, Guan, Huaqing, Zhang, Fan, Gao, Yarong, Teng, Xiaomei, Yang, Weixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663006/
https://www.ncbi.nlm.nih.gov/pubmed/26649145
http://dx.doi.org/10.1155/2016/7263736