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Vinculin Interacts with the Chlamydia Effector TarP Via a Tripartite Vinculin Binding Domain to Mediate Actin Recruitment and Assembly at the Plasma Membrane

The mammalian protein vinculin is often a target of bacterial pathogens to subvert locally host cell actin dynamics. In Chlamydia infection, vinculin has been implicated in RNA interference screens, but the molecular basis for vinculin requirement has not been characterized. In this report, we show...

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Detalles Bibliográficos
Autores principales: Thwaites, Tristan R., Pedrosa, Antonio T., Peacock, Thomas P., Carabeo, Rey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663276/
https://www.ncbi.nlm.nih.gov/pubmed/26649283
http://dx.doi.org/10.3389/fcimb.2015.00088