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Mechanisms of Drug Resistance in Relapse and Refractory Multiple Myeloma
Multiple myeloma (MM) is a hematological malignancy that remains incurable because most patients eventually relapse or become refractory to current treatments. Although the treatments have improved, the major problem in MM is resistance to therapy. Clonal evolution of MM cells and bone marrow microe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663284/ https://www.ncbi.nlm.nih.gov/pubmed/26649299 http://dx.doi.org/10.1155/2015/341430 |