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Investigation of Fatty Acid Ketohydrazone Modified Liposome's Properties as a Drug Carrier

pH-responsive liposomes were prepared by modifying the liposome with acid-cleaving amphiphiles. Palmitic ketohydrazone (P-KH) or stearic ketohydrazone (S-KH), composed of hydrophilic sugar headgroup and hydrophobic acyl chain, was used as a modifier of the DMPC liposome. Because the ketohydrazone gr...

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Detalles Bibliográficos
Autores principales: Hayashi, Keita, Kiriishi, Madoka, Suga, Keishi, Okamoto, Yukihiro, Umakoshi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663332/
https://www.ncbi.nlm.nih.gov/pubmed/26649201
http://dx.doi.org/10.1155/2015/481670