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Indolic Uremic Solutes Enhance Procoagulant Activity of Red Blood Cells through Phosphatidylserine Exposure and Microparticle Release

Increased accumulation of indolic uremic solutes in the blood of uremic patients contributes to the risk of thrombotic events. Red blood cells (RBCs), the most abundant blood cells in circulation, may be a privileged target of these solutes. However, the effect of uremic solutes indoxyl sulfate (IS)...

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Detalles Bibliográficos
Autores principales: Gao, Chunyan, Ji, Shuting, Dong, Weijun, Qi, Yushan, Song, Wen, Cui, Debin, Shi, Jialan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663509/
https://www.ncbi.nlm.nih.gov/pubmed/26516916
http://dx.doi.org/10.3390/toxins7114390