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The Marine-Derived Kinase Inhibitor Fascaplysin Exerts Anti-Thrombotic Activity
Background: The marine-derived kinase inhibitor fascaplysin down-regulates the PI3K pathway in cancer cells. Since this pathway also plays an essential role in platelet signaling, we herein investigated the effect of fascaplysin on thrombosis. Methods: Fascaplysin effects on platelet activation, pla...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663553/ https://www.ncbi.nlm.nih.gov/pubmed/26569265 http://dx.doi.org/10.3390/md13116774 |