The Marine-Derived Kinase Inhibitor Fascaplysin Exerts Anti-Thrombotic Activity

Background: The marine-derived kinase inhibitor fascaplysin down-regulates the PI3K pathway in cancer cells. Since this pathway also plays an essential role in platelet signaling, we herein investigated the effect of fascaplysin on thrombosis. Methods: Fascaplysin effects on platelet activation, pla...

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Detalles Bibliográficos
Autores principales: Ampofo, Emmanuel, Später, Thomas, Müller, Isabelle, Eichler, Hermann, Menger, Michael D., Laschke, Matthias W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663553/
https://www.ncbi.nlm.nih.gov/pubmed/26569265
http://dx.doi.org/10.3390/md13116774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663553/
https://www.ncbi.nlm.nih.gov/pubmed/26569265
http://dx.doi.org/10.3390/md13116774

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