Lovastatin blocks Kv1.3 channel in human T cells: a new mechanism to explain its immunomodulatory properties

Lovastatin is a member of Statins, which are beneficial in a lot of immunologic cardiovascular diseases and T cell-mediated autoimmune diseases. Kv1.3 channel plays important roles in the activation and proliferation of T cells, and have become attractive target for immune-related disorders. The pre...

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Detalles Bibliográficos
Autores principales: Zhao, Ning, Dong, Qian, Qian, Cheng, Li, Sen, Wu, Qiong-Feng, Ding, Dan, Li, Jing, Wang, Bin-Bin, Guo, Ke-fang, Xie, Jiang-jiao, Cheng, Xiang, Liao, Yu-Hua, Du, Yi-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663632/
https://www.ncbi.nlm.nih.gov/pubmed/26616555
http://dx.doi.org/10.1038/srep17381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663632/
https://www.ncbi.nlm.nih.gov/pubmed/26616555
http://dx.doi.org/10.1038/srep17381

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