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Transcriptome analysis of human OXR1 depleted cells reveals its role in regulating the p53 signaling pathway

The oxidation resistance gene 1 (OXR1) is crucial for protecting against oxidative stress; however, its molecular function is unknown. We employed RNA sequencing to examine the role of human OXR1 for genome wide transcription regulation. In total, in non-treated and hydrogen peroxide exposed HeLa ce...

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Detalles Bibliográficos
Autores principales: Yang, Mingyi, Lin, Xiaolin, Rowe, Alexander, Rognes, Torbjørn, Eide, Lars, Bjørås, Magnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663793/
https://www.ncbi.nlm.nih.gov/pubmed/26616534
http://dx.doi.org/10.1038/srep17409