Cargando…
Alkanols inhibit voltage-gated K(+) channels via a distinct gating modifying mechanism that prevents gate opening
Alkanols are small aliphatic compounds that inhibit voltage-gated K(+) (K(v)) channels through a yet unresolved gating mechanism. K(v) channels detect changes in the membrane potential with their voltage-sensing domains (VSDs) that reorient and generate a transient gating current. Both 1-Butanol (1-...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663795/ https://www.ncbi.nlm.nih.gov/pubmed/26616025 http://dx.doi.org/10.1038/srep17402 |