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Plectin isoform 1-dependent nuclear docking of desmin networks affects myonuclear architecture and expression of mechanotransducers

Plectin is a highly versatile cytoskeletal protein that acts as a mechanical linker between intermediate filament (IF) networks and various cellular structures. The protein is crucial for myofiber integrity. Its deficiency leads to severe pathological changes in skeletal muscle fibers of patients su...

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Detalles Bibliográficos
Autores principales: Staszewska, Ilona, Fischer, Irmgard, Wiche, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664173/
https://www.ncbi.nlm.nih.gov/pubmed/26487297
http://dx.doi.org/10.1093/hmg/ddv438