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The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene

The level of susceptibility to tuberculosis (TB) infection depends upon allelic variations in numerous interacting genes. In our mouse model system, the whole-genome quantitative trait loci (QTLs) scan revealed three QTLs involved in TB control on chromosomes 3, 9, and in the vicinity of the H2 comp...

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Detalles Bibliográficos
Autores principales: Logunova, Nadezhda, Korotetskaya, Maria, Polshakov, Vladimir, Apt, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664271/
https://www.ncbi.nlm.nih.gov/pubmed/26618355
http://dx.doi.org/10.1371/journal.pgen.1005672