Distinct Roles for CdtA and CdtC during Intoxication by Cytolethal Distending Toxins

Cytolethal distending toxins (CDTs) are heterotrimeric protein exotoxins produced by a diverse array of Gram-negative pathogens. The enzymatic subunit, CdtB, possesses DNase and phosphatidylinositol 3-4-5 trisphosphate phosphatase activities that induce host cell cycle arrest, cellular distension an...

Descripción completa

Detalles Bibliográficos
Autores principales: Dixon, Shandee D., Huynh, Melanie M., Tamilselvam, Batcha, Spiegelman, Lindsey M., Son, Sophia B., Eshraghi, Aria, Blanke, Steven R., Bradley, Kenneth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664275/
https://www.ncbi.nlm.nih.gov/pubmed/26618479
http://dx.doi.org/10.1371/journal.pone.0143977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664275/
https://www.ncbi.nlm.nih.gov/pubmed/26618479
http://dx.doi.org/10.1371/journal.pone.0143977

Ejemplares similares